Is autism driven by epilepsy in infants with Tuberous Sclerosis Complex?

Romina MoaveroKatarzyna KotulskaLieven LagaeArianna BenvenutoLeonardo Emberti GialloretiBernhard WeschkeKate RineyMartha FeuchtPavel KrsekRima NabboutAnna C JansenKonrad WojdanJulita BorkowskaKrzysztof SadowskiChristoph HertzbergMonique M Van SchooneveldSharon SamueliAlice MaulisovàEleonora AronicaDavid J KwiatkowskiFloor E JansenSergiusz JozwiakPaolo Curatolonull null

Published in: Annals of clinical and translational neurology (2020)

This study confirms a relationship between epilepsy and risk of ASD/DD. However, in this combined randomized/open label study, early treatment with vigabatrin did not alter the risk of ASD or DD at age 2 years.

Keyphrases

open label
autism spectrum disorder
intellectual disability
attention deficit hyperactivity disorder
clinical trial
phase iii
randomized controlled trial
phase ii
study protocol
combination therapy
replacement therapy