Loss of toll-like receptor 5 potentiates spontaneous hepatocarcinogenesis in farnesoid X receptor-deficient mice.
Rachel M GolonkaBeng San YeohPiu SahaAmira GoharaRamakumar TummalaStanislaw StepkowskiAmit K TiwariBina JoeFrank J GonzalezAndrew T GewirtzMatam Vijay-KumarPublished in: Hepatology communications (2023)
Collectively, introducing gut microbiota dysbiosis by TLR5 deletion exacerbated hepatocarcinogenesis in the FxrKO mouse model.