Identification of the Molecular Components of Enhancer-Mediated Gene Expression Variation in Multiple Tissues Regulating Blood Pressure.
Or YaacovPrabhu MathiyalaganHanna E Berk-RauchSanthi K GaneshLuke ZhuThomas J HoffmannCarlos IribarrenNeil RischDongwon LeeAravinda ChakravartiPublished in: Hypertension (Dallas, Tex. : 1979) (2024)
Our work demonstrates the power of tissue-restricted comprehensive CRE analysis, followed by CRE-based expression prediction, for understanding BP regulation in relevant tissues and provides dual-modality supporting evidence, CRE and expression, for the causality genes.