Survival bias may explain the appearance of the obesity paradox in hip fracture patients.
R M AminM RaadS S RaoF MusharbashM J BestDerek F AmanatullahPublished in: Osteoporosis international : a journal established as result of cooperation between the European Foundation for Osteoporosis and the National Osteoporosis Foundation of the USA (2021)
Our data suggest that obesity is a risk factor for mortality in low-energy hip fracture patients, but the appearance of the "obesity paradox" in elderly hip fracture patients results from statistical bias that is only evident upon subgroup analysis.
Keyphrases
- hip fracture
- end stage renal disease
- newly diagnosed
- chronic kidney disease
- ejection fraction
- metabolic syndrome
- type diabetes
- insulin resistance
- weight loss
- peritoneal dialysis
- prognostic factors
- randomized controlled trial
- cardiovascular disease
- weight gain
- electronic health record
- coronary artery disease
- risk factors
- high fat diet induced
- artificial intelligence
- open label