Systemic conbercept pharmacokinetics and VEGF pharmacodynamics following intravitreal injections of conbercept in patients with retinopathy of prematurity.

Yong ChengShuang SunXun DengXuemei ZhuDandan LinghuXiantao SunJianhong Liang

Published in: The British journal of ophthalmology (2021)

Serum VEGF 1 week after IVC was significantly lower than baseline but returned to baseline at 4 weeks. Serum conbercept increased at 1 week and was BLOQ at 4 weeks.

Keyphrases

vascular endothelial growth factor
endothelial cells
gestational age
inferior vena cava
diabetic retinopathy
clinical trial
placebo controlled
randomized controlled trial
platelet rich plasma
age related macular degeneration
double blind