Outcomes of salvage radiation for recurrent world health organization grade II meningiomas: a retrospective cohort study.

Arbaz A MominJianning ShaoPranay SoniJoão Paulo AlmeidaJohn H SuhErin S MurphySamuel T ChaoLilyana AngelovAlireza M MohammadiGene H BarnettPablo F RecinosVarun R Kshettry

Published in: Journal of neuro-oncology (2021)

For salvage radiation of recurrent grade II tumors that are 'radiation-naïve', comparable 3-year PFS rates were found between IMRT and SRS, despite the IMRT group having significantly larger tumors. Salvage radiation overall was less successful in the 're-treatment' cohort compared with the 'radiation-naïve' cohort. Additionally, the effectiveness of radiation significantly declines with successive salvage radiation treatments.

Keyphrases

radiation induced
randomized controlled trial
systematic review
radiation therapy
type diabetes
metabolic syndrome
insulin resistance