Papillary craniopharyngioma in a 4-year-old girl with BRAF V600E mutation: a case report and review of the literature.
R BorrillE CheesmanS StivarosI D Kamaly-AslK GnanalinghamJohn-Paul KildayPublished in: Child's nervous system : ChNS : official journal of the International Society for Pediatric Neurosurgery (2018)
This is the youngest case published to date of papillary craniopharyngioma with a confirmed BRAF V600E mutation. The case encourages discussion about the most appropriate adjuvant therapy for tumor progression in such cases, given the risks of radiotherapy to the developing brain and the increasing availability of oral BRAF inhibitor therapy.