A systematic review of clinical study evidence for pulmonary vasodilator therapy following surgery with cardiopulmonary bypass in children with CHD.
Henry P FooteChristoph P HornikKevin D HillAlexandre T RottaKaran R KumarElizabeth J ThompsonPublished in: Cardiology in the young (2022)
Studies were predominantly single-centre, a control arm was rarely used in randomised studies, and haemodynamic endpoints varied significantly. Further research is needed to reduce post-operative morbidity and mortality from pulmonary hypertension in children with CHD.