Pharmacological administration of 3α,5α-THP into the nucleus accumbens core increases 3α,5α-THP expression and reduces alcohol self-administration.
Laura C OrnelasGiorgia BoeroKalynn Van VoorhiesTodd K O'BuckleyJoyce BesheerA Leslie MorrowPublished in: Alcoholism, clinical and experimental research (2023)
Our results show that local increases in 3α,5α-THP in the AcbC may alter mesolimbic activity that drives a reduction in alcohol self-administration.