Two-year outcomes of low-exposure extended-release tacrolimus and mycophenolate mofetil regimen in de novo kidney transplantation: A multi-center randomized controlled trial.
Yuji HidakaNorihiko GotoShigeyoshi YamanagaKohei KinoshitaKosuke TanakaChiaki KawabataMariko ToyodaToshihide TomosugiKenta FutamuraManabu OkadaMakoto TsujitaTakahisa HiramitsuHiroshi YokomizoAkira MiyataShunji NarumiTakaaki KobayashiYoshihiko WataraiPublished in: Clinical transplantation (2022)
Although the LE TACER regimen showed similar rates of acute rejection, as well as graft and patient survival compared with SE after KTx, LE was significantly more associated with dnDSA. Further investigation of its long-term effect on graft survival is warranted. (University Hospital Medical Information Network Clinical Trials Registry ID: UMIN000033089).