IImpact of using less objective symptoms to define tolerated dose during food challenges: a data-driven approach.
Paul J TurnerNandinee PatelKatharina BlumchenStefanie BerkesHugh A SampsonKirsten Beyer
Published in: The Journal of allergy and clinical immunology (2023)
The use of less objective symptoms to define challenge-stop compromises the reproducibility of FC as a tool to assess efficacy outcomes in interventional studies, and potentially over-estimates the efficacy of the intervention tested.