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Bidirectional hybrid erythritol-inducible promoter for synthetic biology in Yarrowia lipolytica.

Lea VidalEsteban LebrunYoung-Kyoung ParkGuillaume MottetJean-Marc Nicaud
Published in: Microbial cell factories (2023)
In this research, we developed novel bidirectional and hybrid bidirectional promoters of which expression can be fine-tuned, responding to the need for versatile promoters in the yeast Y. lipolytica. This study provides effective tools that can be employed to smoothly adjust the erythritol-inducible co-expression of two target genes in biotechnology applications. BDPs developed in this study have potential applications in the fields of heterologous protein production, metabolic engineering, and synthetic biology.
Keyphrases
  • poor prognosis
  • binding protein
  • gene expression
  • dna methylation
  • transcription factor
  • long non coding rna
  • protein protein