Ivabradine in heart failure patients with reduced ejection fraction and history of paroxysmal atrial fibrillation.
Yung-Lung ChenJeng-Yu JanJung-Jung ChangMing-Shyan LinTeng-Yao YangPo-Chang WangMien-Cheng ChenPublished in: ESC heart failure (2022)
Ivabradine treatment was associated with an increased risk of HF hospitalization in symptomatic HFrEF patients with a history of paroxysmal AF. Further prospective randomized studies are warranted.
Keyphrases
- atrial fibrillation
- heart failure
- catheter ablation
- oral anticoagulants
- left atrial
- left atrial appendage
- heart rate
- direct oral anticoagulants
- double blind
- percutaneous coronary intervention
- open label
- acute heart failure
- placebo controlled
- phase iii
- randomized controlled trial
- left ventricular
- cardiac resynchronization therapy
- venous thromboembolism
- replacement therapy