Home-based intensive nutrition therapy improves frailty and sarcopenia in patients with decompensated cirrhosis: A randomized clinical trial.
Babu Lal MeenaSunil TanejaPuneeta TandonNancy SahniRaghuraman SoundararajanUjjwal GorsiArka DeNipun VermaMadhumita PremkumarAjay Kumar DusejaRadha K DhimanVirendra SinghPublished in: Journal of gastroenterology and hepatology (2022)
In patients with decompensated cirrhosis, frailty, and sarcopenia, a 6-month dietitian-supported home-based intensive outpatient nutrition therapy was associated with statistically and clinically relevant improvement in frailty. The subgroup of adherent patients showed improvement in their liver disease scores and reduction in mortality. These findings support the key role of food as medicine in the management of cirrhosis.
Keyphrases
- community dwelling
- ejection fraction
- heart failure
- end stage renal disease
- physical activity
- skeletal muscle
- newly diagnosed
- chronic kidney disease
- prognostic factors
- peritoneal dialysis
- randomized controlled trial
- risk factors
- type diabetes
- cardiovascular disease
- risk assessment
- coronary artery disease
- climate change
- patient reported