Quality of life in patients with CRB1-associated retinal dystrophies: A longitudinal study.
Jessica S KaruntuXuan-Thanh-An NguyenMays TalibMary J van SchooneveldJan WijnholdsMaria M van GenderenNicoline E Schalij-DelfosCaroline C W KlaverMagda A Meester-SmoorL Ingeborgh van den BornCarel B HoyngAlberta A H J ThiadensArthur A BergenRuth M A van NispenCamiel J F BoonPublished in: Acta ophthalmologica (2023)
In the absence of an intervention, a decline in vision-related quality of life is present in patients with pathogenic CRB1 variants at 4-year follow-up. Patient-reported outcome measures should be included in future clinical trials, as they can be a potential indicator of disease progression and treatment efficacy.