Identification of RAD51 foci in cancer-associated circulating cells of patients with high-grade serous ovarian cancer: association with treatment outcomes.

Zena AlizziSayeh SaraviSaira KhaliqueThirza McDonaldEmmanouil KarterisMarcia Hall

Published in: International journal of gynecological cancer : official journal of the International Gynecological Cancer Society (2023)

Levels of RAD51 foci in circulating cancer-associated cells of patients with high-grade serous ovarian cancer are associated with clinical outcomes and may be a more pragmatic method of determining a homologous repair-deficient population.

Keyphrases

high grade
low grade
induced apoptosis
dna damage
dna repair
cell cycle arrest
endoplasmic reticulum stress
oxidative stress
clinical trial
randomized controlled trial
signaling pathway
study protocol