Visible-light-promoted 3,5-dimethoxyphenyl glycoside activation and glycosylation.
Yafei CaoMinmin ZhouRun-Ze MaoYou ZouFeng XiaDa-Ke LiuJianhui LiuQin LiDe-Cai XiongXin-Shan YePublished in: Chemical communications (Cambridge, England) (2021)
A new glycosylation method promoted by visible light with 3,5-dimethoxyphenyl glycoside as the donor was developed. This protocol delivers both O-glycosides and N-glycosides in moderate to excellent yields using a wide range of O-nucleophiles and nucleobases as the glycosyl acceptors.