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Effectiveness of non-pharmacological therapies for chronic pain in people with autoimmune diseases in Africa: A protocol for a systematic review and meta-analysis.

Gebreamlak Gebremedhn GebremeskelTeklehaimanot Gereziher HaileGebremeskel Tukue GebrewahdAbrha HailayWoldu AberheGuesh MebrahtomKidane ZereabrukAssefa Iyasu NegashHailemikael GebrekidanDegena Bahrey Tadesse
Published in: PloS one (2024)
This review protocol has been registered in the International Prospective Register of Systematic Reviews (PROSPERO, CRD42023449896). Electronic databases (PubMed, Africa Index Medicus, Cochrane Library, CINAHL, PsycINFO, and Web of Science) will be used for searching published articles. The study will use R for data synthesis, employing a random-effects meta-analysis approach to calculate pooled effect sizes, assess heterogeneity using the I2 statistic, and evaluate publication bias. In conclusion, this protocol aims to fill the knowledge gap on non-pharmacological therapies for chronic pain in patients with autoimmune diseases in Africa. It will potentially enhance evidence-based decision-making to improve pain management and, hence, the quality of life of people with autoimmune diseases in Africa.
Keyphrases
  • chronic pain
  • pain management
  • systematic review
  • randomized controlled trial
  • meta analyses
  • decision making
  • healthcare
  • public health
  • big data
  • machine learning
  • artificial intelligence
  • case control
  • open label