Genome-Wide Association Study of Chronic Kidney Disease Progression.

C Robinson-CohenJ L TriozziB RowanJ HeH C ChenN S ZhengW Q WeiO D WilsonJ N HellwegeP S TsaoJ M GazianoA BickM E MathenyC P ChungL LipworthE D SiewT A IkizlerR TaoAdriana M Hung

Published in: Journal of the American Society of Nephrology : JASN (2023)

Three loci were significantly associated with longitudinal eGFR change at genome-wide significance. These findings help characterize molecular mechanisms of eGFR decline and may contribute to development of new therapeutic approaches for progressive CKD.

Keyphrases

genome wide association study
chronic kidney disease
genome wide
small cell lung cancer
epidermal growth factor receptor
end stage renal disease
tyrosine kinase
dna methylation
multiple sclerosis
copy number
cross sectional
peritoneal dialysis