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Effects of particulate matter on atherosclerosis: a link via high-density lipoprotein (HDL) functionality?

Siri A N HolmeTorben SigsgaardJørn A HolmeGitte Juel Holst
Published in: Particle and fibre toxicology (2020)
Current literature suggests that PM promotes HDL dysfunction via oxidative pathways. However, as relatively few studies so far have evaluated the impact of particulate air pollution on HDL functionality, more human epidemiological as well as experimental studies are needed to strengthen any possible causal relationship and determine any relevance to atherosclerosis.
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