Prediction of bleb formation in intracranial aneurysms using machine learning models based on aneurysm hemodynamics, geometry, location, and patient population.
Seyedeh Fatemeh Salimi AshkezariFernando MutMartin SlawskiBoyle ChengAlexander K YuTimothy G WhiteHenry H WooMatthew J KochSepideh Amin-HanjaniFady T CharbelBehnam Rezai JahromiMika NiemeläTimo KoivistoJuhana FrosenYasutaka TobeSpandan MaitiAnne M RobertsonJuan R CebralPublished in: Journal of neurointerventional surgery (2021)
Based on the premise that aneurysm characteristics prior to bleb formation resemble those derived from vascular reconstructions with their blebs virtually removed, machine learning models can identify aneurysms prone to bleb development with good accuracy. Pending further validation with longitudinal data, these models may prove valuable for assessing the propensity of IAs to progress to vulnerable states and potentially rupturing.