LncRNA H19 promotes odontoblastic differentiation of human dental pulp stem cells by regulating miR-140-5p and BMP-2/FGF9.

Jialin Zhong Xinran TuYuanyuan KongLiyang GuoBaishun LiWenchao ZhongYing ChengYiguo JiangQianzhou Jiang

Published in: Stem cell research & therapy (2020)

Our data revealed that H19 plays a positive regulatory role in odontoblastic differentiation of hDPSCs through miR-140-5p/BMP-2/FGF9 axis, suggesting that H19 may be a stimulatory regulator of odontogenesis.

Keyphrases

stem cells
mesenchymal stem cells
endothelial cells
transcription factor
bone regeneration
electronic health record
single cell
big data
cell therapy
pluripotent stem cells
long noncoding rna
artificial intelligence