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Placebo and nocebo responses in randomized controlled trials of non-tumor necrosis factor biologics and Janus kinase inhibitors in patients with active rheumatoid arthritis showing insufficient response to tumor necrosis factor inhibitors: A meta-analysis.

Yoon-Kyoung SungYoung Ho Lee
Published in: Zeitschrift fur Rheumatologie (2021)
There were higher placebo and less nocebo effects of JAK vs. non-TNF inhibitors in RA patients with an insufficient response to TNF inhibitors, and the greater the placebo response, the weaker the nocebo response and the greater the efficacy.
Keyphrases
  • rheumatoid arthritis
  • disease activity
  • double blind
  • interstitial lung disease
  • randomized controlled trial
  • ankylosing spondylitis
  • systematic review
  • systemic lupus erythematosus
  • systemic sclerosis