Multicolor flow cytometric analysis of TLR2 and TLR9 expression and function in NK cells from patients with ANCA-associated vasculitis.

Rossana ScrivoGiovanna PeruzziAngelica GattamelataCatharina C GrossRaffaella CarlettiCira Di GioiaJessica BrandtRoberta PrioriStefania MorroneAngela SantoniGuido Valesini

Published in: Cytometry. Part B, Clinical cytometry (2017)

Our data suggest a role of infectious stimuli triggering NK cells in AAV pathogenesis. Poor detection of NK cells in affected tissues suggests a marginal involvement in local inflammatory responses. © 2017 International Clinical Cytometry Society.

Keyphrases

nk cells
toll like receptor
inflammatory response
immune response
poor prognosis
gene expression
electronic health record
nuclear factor
single cell
big data
loop mediated isothermal amplification
binding protein
data analysis
artificial intelligence
deep learning
sensitive detection