Reduced endogenous secretory RAGE in blood and bronchoalveolar lavage fluid is associated with poor prognosis in idiopathic pulmonary fibrosis.
Kakuhiro YamaguchiHiroshi IwamotoWitold MazurShinichiro MiuraShinjiro SakamotoYasushi HorimasuTakeshi MasudaShintaro MiyamotoTaku NakashimaShinichiro OhshimoKazunori FujitakaHironobu HamadaNoboru HattoriPublished in: Respiratory research (2020)
Decreased esRAGE levels in BALF and blood were associated with poor prognoses in patients with IPF. These results suggest that esRAGE could be related to the pathophysiology of IPF and serum esRAGE could be a potential prognostic marker of IPF.