FOXA1 of regulatory variant associated with risk of breast cancer through allele-specific enhancer in the Chinese population.

Bin LiXiang ChengYing ZhuHao WanZequn LuYimin CaiWenhui LiPengfei YiLi LiuJiang ChangXiaoping MiaoJianbo TianRong Zhong

Published in: Breast cancer (Tokyo, Japan) (2021)

Our study suggested that the regulatory variant rs7160774 was associated with risk of breast cancer by long-range modulating FOXA1 expression and provided critical insights into pinpoint causal genetic variants.

Keyphrases

transcription factor
poor prognosis
binding protein
signaling pathway
young adults
long non coding rna