Cow's milk allergy skin tests: fresh milk, commercial extracts, or both?

Idit Lachover-RothNadav GiornoTzipi Hornik-LurieAnat Cohen-EnglerYossi RosmanKeren Meir-ShafrirRonit Confino-Cohen

Published in: Allergy, asthma, and clinical immunology : official journal of the Canadian Society of Allergy and Clinical Immunology (2023)

SPT with CE for CMA evaluation is more reliable than SPT performed with fresh milk. In patients suspected of having IgE-mediated CMA, before deciding on performing OFC, it is advised to perform SPT with at least two different extracts, and always include casein. Fresh milk can serve as a backup if commercial extracts are not available. In cases that the SPT with fresh milk is 3 mm or less, there is 93.3% chance that the OFC will pass without reaction. Trial registration This study protocol was reviewed and approved by the Ethics Committee of Meir Medical Center, IRB Number 0083-18 MMC.

Keyphrases

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end stage renal disease
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randomized controlled trial
newly diagnosed
public health
peritoneal dialysis
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machine learning
soft tissue
open label
big data
energy transfer