Uric Acid Expression in Carotid Atherosclerotic Plaque and Serum Uric Acid Are Associated With Cerebrovascular Events.

Valentina NardiFederico FranchiMegha PrasadErica M FaticaMariam P AlexanderMelanie C BoisJosephine LamRavinder J SinghFredric B MeyerGiuseppe LanzinoYuning XiongEsther LutgensLilach Orly LermanAmir Lerman

Published in: Hypertension (Dallas, Tex. : 1979) (2022)

The current study supports a potential role of UA as a potential tissue participant and a systemic biomarker in the pathogenesis of carotid atherosclerosis. UA may provide a mechanistic explanation for plaque instability and subsequent ischemic cerebrovascular events.

Keyphrases

uric acid
metabolic syndrome
coronary artery disease
poor prognosis
cardiovascular disease
type diabetes
ischemia reperfusion injury