Effects of multidisciplinary therapy on physical function in Huntington's disease.

Travis M CruickshankAlvaro P ReyesLuis E PenaililloTim PulverentiDanielle M BartlettPauline ZaenkerAnthony J BlazevichRobert U NewtonJennifer A ThompsonJohnny LoMel R Ziman

Published in: Acta neurologica Scandinavica (2018)

Our findings suggest that outpatient multidisciplinary therapy has positive effects on manual dexterity and muscle strength, but no meaningful effects on mobility, balance, cardiorespiratory endurance and upper extremity muscle strength in patients with HD. Larger randomized controlled trials are needed to confirm these preliminary findings.

Keyphrases

randomized controlled trial
high intensity
skeletal muscle
body composition
quality improvement
stem cells
resistance training
cell therapy
smoking cessation
replacement therapy
meta analyses