START CARE: a protocol for a randomised controlled trial of step-wise budesonide-formoterol reliever-based treatment in children.

Tasmin BarryMark HollidayJenny SparksRowan BiggsAtalie ColmanRebekah LambKaren OldfieldNick ShorttKyley KerseJohn MartindaleAllie EathorneMichaela WaltonBianca BlackMatire HarwoodPepa BruceRuth SempriniAndrew BushLouise J FlemingCatherine A ByrnesDavid McNamaraLee HatterStuart R DalzielMark WeatherallRichard Beasley

Published in: ERJ open research (2024)

This will be the first RCT to compare the efficacy and safety of a step-wise budesonide-formoterol reliever alone or MART regimen with conventional inhaled ICS or ICS-long-acting β-agonist maintenance plus SABA reliever in children. The results will provide a much-needed evidence base for the treatment of asthma in children.

Keyphrases

young adults
healthcare
randomized controlled trial
chronic obstructive pulmonary disease
palliative care
cystic fibrosis
lung function
quality improvement
air pollution
pain management