Association between IL-8 (-251T/A) and IL-6 (-174G/C) Polymorphisms and Oral Cancer Susceptibility: A Systematic Review and Meta-Analysis.

Farzad RezaeiHady MohammadiMina HeydariMasoud SadeghiHamid Reza MozaffariAtefeh KhavidMostafa GodinySerge BrandKenneth M DürstelerAnnette Beatrix BrühlDominik CordierDena Sadeghi Bahmani

Published in: Medicina (Kaunas, Lithuania) (2021)

The meta-analysis confirmed that there was no association between the polymorphisms of IL-6 (-174G/C) and IL-8 (-251T/A) and the susceptibility of OC. However, the source of control and the genotyping method could unfavorably impact on the association between the polymorphisms of IL-6 (-174G/C) and the risk OC.

Keyphrases

systematic review
randomized controlled trial
gene expression
genome wide
dna methylation
single cell
case control