Choice of HbA1c threshold for identifying individuals at high risk of type 2 diabetes and implications for diabetes prevention programmes: a cohort study.
Lauren R RodgersAnita V HillJohn M DennisZoe CraigBenedict MayAndrew T HattersleyTimothy J McDonaldRob C AndrewsAngus JonesBeverley M ShieldsPublished in: BMC medicine (2021)
A large proportion of people are identified as high-risk using current thresholds. Increasing the risk threshold markedly reduces the number of people that would be classified as high-risk and entered into prevention programmes, although this must be balanced against cases missed. Raising the entry threshold would allow limited intervention opportunities to be focused on those most likely to develop T2D.