'Low' faecal immunochemical test (FIT) colorectal cancer: a 4-year comparison of the Nottingham '4F' protocol with FIT10 in symptomatic patients.
James A BaileyAlastair James MortonJ JonesC J ChapmanS OliverJ R MorlingH PatelDavid J HumesAyan BanerjeaPublished in: Colorectal disease : the official journal of the Association of Coloproctology of Great Britain and Ireland (2024)
A combination of FIT with blood results and DRE (the 4F protocol) reduced the risk of missed or delayed diagnosis. Further studies on the impact of such protocols on the diagnostic accuracy of FIT are expected. The value of adding blood tests to FIT may be restricted to specific parts of the fHb results spectrum.