Transcatheter Mitral Valve Repair and Replacement: Current Evidence for Intervention and the Role of CT in Preprocedural Planning-A Review for Radiologists and Cardiologists Alike.
Paul MaggioreMalcolm AnastasiusAlex L HuangPhilipp BlankeJonathan A LeipsicPublished in: Radiology. Cardiothoracic imaging (2020)
The mitral valve is a complex structure with a three-dimensional saddle shape annulus. Mitral regurgitation occurs from leaflet coaptation failure that is either primary (a problem with the leaflets) or secondary (chamber dilatation in the setting of cardiomyopathy). There has been an increase in focus on transcatheter mitral valve interventions, for both mitral repair and replacement. These technologies have rapidly developed to provide treatment for a substantial number of patients with severe symptomatic mitral regurgitation who are at too high of a risk to undergo open heart surgery. CT assessment of the mitral valve has developed with equal rapidity, with regard to preprocedural planning for transcatheter therapies. This review will provide an overview of mitral valve anatomy, an update on the current transcatheter repair and replacement therapies, as well as a focused overview of the role of multislice CT in mitral assessment prior to intervention. © RSNA, 2020.
Keyphrases
- mitral valve
- left atrial
- image quality
- dual energy
- computed tomography
- left ventricular
- minimally invasive
- contrast enhanced
- randomized controlled trial
- heart failure
- positron emission tomography
- magnetic resonance imaging
- physical activity
- coronary artery bypass
- early onset
- magnetic resonance
- diffusion weighted imaging
- surgical site infection
- combination therapy
- percutaneous coronary intervention