Failure of fat cell proliferation, mitochondrial function and fat oxidation results in ectopic fat storage, insulin resistance and type II diabetes mellitus.
L HeilbronnS R SmithE RavussinPublished in: International journal of obesity and related metabolic disorders : journal of the International Association for the Study of Obesity (2005)
The novel paradigms of ectopic fat and fat cell as an endocrine organ probably will constitute a new framework for the study of the links between our obesigenic environment and the risk of developing diabetes.