Vitamin D status influences cytokine production and MALAT1 expression from the PBMCs of patients with coronary artery disease and healthy controls.
Peyman Nowrouzi-SohrabiMehdi KalaniPeyman IzadpanahHassan AhmadvandMasoumeh FakhourReza FadaeiMeghdad KhorshidifarAtefeh SeghatoleslamPublished in: Revista da Associacao Medica Brasileira (1992) (2021)
Given that in vitamin D deficient individuals a decreased level of MALAT1 was associated with CD36 expression and increased IL-22 production, vitamin D supplementation may play a role in reducing MALAT1/CD36/IL-22 mediated complications such as T2DM and CAD, especially in vitamin D deficiency.