Effectiveness of dose-dense methotrexate, vinblastine, doxorubicin, and cisplatin as compared to gemcitabine-based regimens as neoadjuvant chemotherapy for oncologic outcomes in muscle-invasive bladder cancer cases-Single-center study in Japan.
Yozo MitsuiMizuho OkawaShunsuke HoriMasato UetaniMizuki KasaharaFumito YamabeHideyuki KobayashiKoichi NagaoKoichi NakajimaPublished in: International journal of urology : official journal of the Japanese Urological Association (2024)
The present study is the first to show that dd-MVAC as NAC can provide better survival as compared with a gemcitabine-based regimen for patients with MIBC treated in Japan.
Keyphrases
- neoadjuvant chemotherapy
- locally advanced
- rectal cancer
- muscle invasive bladder cancer
- squamous cell carcinoma
- lymph node
- sentinel lymph node
- randomized controlled trial
- radiation therapy
- systematic review
- high dose
- drug delivery
- prostate cancer
- cancer therapy
- adipose tissue
- low dose
- insulin resistance
- metabolic syndrome
- skeletal muscle
- minimally invasive