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The proposed modification of TNM staging and therapeutic strategy for skip metastasis in papillary thyroid carcinoma: A multicenter retrospective cohort study.

Zheyu YangYu HengQiwu ZhaoDing HaoLei TaoXiaxing DengWei CaiWeihua Qiu
Published in: Cancer medicine (2023)
In conclusion, our study indicated that, among patients with LLNM, those with positive skip metastasis showed significantly lower recurrence, exhibiting a similar rucurrence tendency as patients with CLNM. Thus, skip metastasis could be categorized into N1a stage rather than N1b stage based on the AJCC TNM staging system. The downstaging of skip metastasis may reveal more conservative treatment strategy.
Keyphrases
  • lymph node
  • squamous cell carcinoma
  • pet ct
  • gene expression
  • clinical trial
  • cross sectional
  • lymph node metastasis
  • free survival
  • genome wide