Mining reported adverse events induced by potential opioid-drug interactions.
Jinzhao ChenGaoyu WuAndrew MichelsonZachary VesoulisJennifer BognerJohn D CorriganPhilip Richard Orrin PayneFuhai LiPublished in: JAMIA open (2020)
The proposed data analysis and visualization are useful for mining FAERS data to identify novel polypharmacy associated AEs, as shown for ODIs. This approach was successful in recapitulating known drug interactions and also identified new opioid-specific AEs that could impact prescribing practices.