Diabetes, antidiabetic medications and risk of dementia: A systematic umbrella review and meta-analysis.

Alvin Kuate DefoVeselko BakulaAlessandro PisaturoChristopher LabosSimon S WingStella S Daskalopoulou

Published in: Diabetes, obesity & metabolism (2023)

Metformin, thiazolidinediones, pioglitazone, GLP1RAs and SGLT2is were associated with reduced risk of dementia. More longitudinal studies aimed at determining their relative benefit in different populations should be conducted.

Keyphrases

mild cognitive impairment
cognitive impairment
type diabetes
cardiovascular disease
glycemic control
cross sectional
insulin resistance