Within and post-trial effects of an intensive lifestyle intervention on kidney disease in adults with overweight or obesity and type 2 diabetes mellitus: a secondary analysis of the Look AHEAD clinical trial.

William C Knowler Haiying ChenJudy L BahnsonSteven E KahnCora E LewisDavid M NathanRobert G NelsonScott Jordan PillaJohn P Bantlenull null

Published in: BMJ open diabetes research & care (2024)

ILI reduced kidney disease progression during and following the active intervention in persons aged ≥60 years. ILI should be considered for reducing kidney disease incidence in older persons with type 2 diabetes.

Keyphrases

weight loss
clinical trial
randomized controlled trial
physical activity
metabolic syndrome
study protocol
phase ii
weight gain
insulin resistance
type diabetes
glycemic control
risk factors
open label
community dwelling
middle aged
body mass index
skeletal muscle