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Tofacitinib Affects M1-like and M2-like Polarization and Tissue Factor Expression in Macrophages of Healthy Donors and IBD Patients.

Isabelle LethenKristina Lechner-GrimmMichael GabelAnnkathrin KnaussGisela FeltenMarkus F NeurathBenno Weigmann
Published in: Inflammatory bowel diseases (2024)
Tofacitinib influences both polarizations (M1/M2) and the expression of tissue factor in a dose-dependent manner.
Keyphrases
  • poor prognosis
  • rheumatoid arthritis
  • end stage renal disease
  • ulcerative colitis
  • newly diagnosed
  • peritoneal dialysis
  • binding protein
  • patient reported outcomes
  • patient reported