Design of the Building Research in CRC prevention (BRIDGE-CRC) trial: a 6-month, parallel group Mediterranean diet and weight loss randomized controlled lifestyle intervention targeting the bile acid-gut microbiome axis to reduce colorectal cancer risk among African American/Black adults with obesity.
Andrew McLeodPatricia WolfRobert S ChapkinLaurie A DavidsonIvan IvanovMichael BerbaumLauren R WilliamsH Rex GaskinsJason RidlonJen Sanchez-FlackLara BlumsteinLinda SchifferAlyshia HammKate CaresMirjana AntonicBeatriz Penalver BernabeMarian FitzgibbonLisa Tussing-HumphreysPublished in: Trials (2023)
ClinicalTrials.gov NCT04753359 . Registered on 15 February 2021.
Keyphrases
- weight loss
- african american
- phase iii
- phase ii
- bariatric surgery
- open label
- double blind
- roux en y gastric bypass
- clinical trial
- placebo controlled
- randomized controlled trial
- study protocol
- gastric bypass
- cancer therapy
- glycemic control
- metabolic syndrome
- weight gain
- insulin resistance
- type diabetes
- skeletal muscle
- physical activity
- adipose tissue
- high fat diet induced
- body mass index