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Early and sustained Lactobacillus plantarum probiotic therapy in critical illness: the randomised, placebo-controlled, restoration of gut microflora in critical illness trial (ROCIT).

Edward LittonMatt AnsteyDavid BroadhurstAndy ChapmanAndrew CurrieJanet FerrierJoel GummerAlisa HigginsJolene LimLaurens ManningErina MyersKatrina OrrAnne-Marie PalermoAndrea PapariniSusan PellicanoEdward RabyAnu RammohanAdrian RegliBernhard RichterSam SalmanTobias StrunkSharon WatersonDavid WeightBradley WibrowFiona Wood
Published in: Intensive care medicine (2021)
Early and sustained untargeted administration of probiotic therapy with Lactobacillus plantarum 299v to adult patients admitted to the ICU is safe, but not associated with improved patient outcomes.
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