Cell networks in the mouse liver during partial hepatectomy.

Bin LiDaniel Rodrigo-TorresCarl PelzBrendan T InnesPamela CanadaySunghee ChaiPeter ZandstraGary D BaiderMarkus Grompe

Published in: bioRxiv : the preprint server for biology (2023)

A platform predicting cell-cell interactions in liver regeneration was establishedThis platform identified the BMP4 pathway antagonist Fstl1 as a stimulator of hepatocyte proliferationThis platform also discovered the role of Wnt pathway inhibitor Sfrp1 delaying liver regeneration.

Keyphrases

stem cells
single cell
cell therapy
high throughput
cell proliferation
wound healing