Changes of blood-brain-barrier function and transfer of amyloid beta in rats with collagen-induced arthritis.
Po-Hsuan LaiTing-Hsuan WangNai-You ZhangKuo-Chen WuChung-Chen Jane YaoChun-Jung LinPublished in: Journal of neuroinflammation (2021)
Neuroinflammation and the changes of BBB function were observed in CIA rats. The increased RAGE expression at cerebral blood vessels and enhanced blood-to-brain influx of Aβ indicate the imbalanced BBB clearance of Aβ in RA.
Keyphrases
- blood brain barrier
- cerebral ischemia
- rheumatoid arthritis
- poor prognosis
- subarachnoid hemorrhage
- resting state
- diabetic rats
- multiple sclerosis
- functional connectivity
- lps induced
- oxidative stress
- cognitive impairment
- systemic sclerosis
- inflammatory response
- long non coding rna
- drug induced
- wound healing
- idiopathic pulmonary fibrosis