The influence of gastric bypass surgery on the concentration of high mobility group box 1, nuclear factor erythroid 2-related factor 2 and the genes expression of high mobility group box 1, nuclear factor erythroid2-related factor 2, interleukin 6, and tumor necrosis factor-alpha in the peripheral blood mononuclear cells of patients with morbid obesity.
Masouod KhanaghaeiNasrin ZiamajidiJalal PoorolajalGholamreza AsadikaramPayam NikoyanMohammadhosein BajianRoghayeh AbbasalipourkabirPublished in: Molecular biology reports (2022)
Weight loss indicated the significant function of adipose tissue in the induction of oxidative stress and inflammatory factors. Gastric bypass reduced the inflammation conditions and improved the metabolic status and living situations in the patients with morbid obesity.
Keyphrases
- gastric bypass
- weight loss
- nuclear factor
- bariatric surgery
- roux en y gastric bypass
- oxidative stress
- obese patients
- toll like receptor
- adipose tissue
- binding protein
- insulin resistance
- transcription factor
- glycemic control
- weight gain
- dna damage
- minimally invasive
- poor prognosis
- rheumatoid arthritis
- type diabetes
- metabolic syndrome
- coronary artery bypass
- genome wide
- immune response
- inflammatory response
- diabetic rats
- acute coronary syndrome
- high fat diet
- dna methylation
- gene expression
- physical activity
- percutaneous coronary intervention
- genome wide identification
- body mass index
- bioinformatics analysis
- heat shock protein