An adult-based genetic risk score for liver fat associates with liver and plasma lipid traits in children and adolescents.

Yun HuangSara E StinsonHelene Baek JuelMorten A V LundLouise Aas HolmCilius E FonvigTrine NielsenNiels GrarupOluf PedersenMichael ChristiansenElizaveta ChabanovaHenrik S ThomsenAleksander KragStefan StenderJens-Christian HolmTorben Hansen

Published in: Liver international : official journal of the International Association for the Study of the Liver (2023)

The genetic predisposition for liver fat accumulation conferred risk of hepatic steatosis in children and adolescents. The liver fat GRS has potential clinical utility for risk stratification.

Keyphrases

adipose tissue
genome wide
fatty acid
copy number
dna methylation
climate change
human health