A systematic overview of the spermatotoxic and genotoxic effects of methotrexate, ganciclovir and mycophenolate mofetil.

Nicolai B Jensen Signe D Justesen Agnete LarsenErik ErnstLars Henning Petersen

Published in: Acta obstetricia et gynecologica Scandinavica (2021)

Data from human and animal studies indicate transient spermatotoxic and genotoxic potentials of immunosuppressive and cytotoxic doses of MTX. There are a limited number of studies investigating GCV and MMF.

Keyphrases

endothelial cells
case control
high dose
electronic health record
induced pluripotent stem cells
big data
pluripotent stem cells
cerebral ischemia
machine learning
data analysis