Matched analysis of circulating selenium with the breast cancer selenotranscriptome: a multicentre prospective study.
Kamil DemircanYlva BengtssonThilo Samson ChillonJohan Vallon-ChristerssonQian SunChrister LarssonMartin MalmbergLao H SaalLisa RydénÅke BorgJonas ManjerLutz SchomburgPublished in: Journal of translational medicine (2023)
This first unbiased analysis of serum selenium with the breast cancer selenotranscriptome identified an effect-modification of selenium on the associations of DIO1, SELENOM, and DIO3 with prognosis. Selenium substitution in patients with DIO1-expressing tumours merits consideration to improve survival.